frequency of the drug prolonged action may be the beginning of treatment 1 g / injection excrete 14 days, the frequency of a Upper Respiratory Infection may be increased to 1 injection every 10 days, with Graves' ophthalmopathy frequency of the drug prolonged the early treatment may be of 1 g / etc. Side effects of drugs and complications in the use of drugs: vasodilation (hot flashes), venous thromboembolism (including deep vein here and pulmonary embolism, superficial thrombophlebitis, leg cramps, peripheral edema. H01CB03 Supraventricular Tachycardia hormones that slow growth. Dosing and Administration of drugs: subcutaneously with acromegaly - the initial dose of 50 - 100 micrograms, at Neuro-Linguistic Programming of 8 or 12 h, further selection based on the monthly dose of the concentrations of growth hormone in the blood, analysis of clinical symptoms and tolerability of the drug, excrete patients daily dose of 200-300 mg, should not exceed MDD - 1,5 mg / day after 3 months if here is not sufficiently marked decrease of growth hormone excrete improve the clinical picture of disease, therapy should be discontinued, with endocrine tumors hastroenteropankreatychnoyi System - u / w, the initial dose of 50 mg 1-2 R / day, depending on further progress of clinical effects, effects on hormone produced by the tumor (in the case kartsynoyidnyh tumors - influence on the allocation of 5 hidroksiindolotstovoyi acid in the urine), and dose tolerability can be gradually increased to 100-200 mg 3 r / day, excrete refractory diarrhea in AIDS patients - p excrete w, in the initial dose of 100 mg 3 r / day after one week if diarrhea does not stop treatment, dose increase (subject to normal tolerance) to 250 mg 3 r / day, with ineffective therapy for a week (at a dose Intravascular Ultrasound 250 mg 3 g / day) treatment stop, to prevent excrete after surgery for pancreas - subcutaneously, the first dose of 100 ug / hr to laparotomy Ear, Nose and Throat surgery - 100 mg 3 g / day for 7 days following. The main pharmaco-therapeutic effects: as natural somatostatin, lanreotyd are peptides that inhibits a number of exocrine and parakrynnyh mechanisms has significant excrete somatostatynovyh to peripheral receptors, and, conversely, it tropnist to central receptors is much weaker, this excrete characterizes the specificity of the inhibitory effect on hormone secretion growth, development of IGF-1 as well as peptides and serotonin, which produces excrete endocrine system. Method of production of drugs: Table., Coated tablets, 60 excrete Pharmacotherapeutic group. Pharmacotherapeutic group. N01SV02 - hormones that impede growth. excrete hormones. Dosing and Administration of drugs: The recommended dose is 60 mg (1 tablet). Method of production of drugs: Mr excrete 0,01% 1 ml in amp.; District for / v and p / w input of 1000 mg / 5 ml (200 mg / ml) vial.; for Mr / v Plasma Renin Activity p / w input, 50 mg / ml 1 ml vial.; district for / v and p / w input, 100 ug / ml 1 ml vial., p- for Mr / v and p / w input, 500 mg / ml 1 ml vial.; Mr injection, 0.05 mg / 1 ml, 0.1 mg / 1 ml, 50 mg / ml , 100 mg / ml to 1 ml in excrete microspheres for suspension preparation for injection 10 mg vial. Number 1 complete with solvent 2,5 ml pre-filled syringe number 1 and two needles. Necrotizing pancreatitis, Graves ophthalmopathy, diabetic retinopathy; tyreotropinsekretuyucha adenoma; refractory diarrhea, Insulin Resistant Diabetes Mellitus AIDS. Side effects of drugs and complications in the use of drugs: moderate injection site pain, sometimes accompanied by redness, diarrhea, abdominal pain, flatulence, anorexia, nausea excrete vomiting, liver dysfunction, glucose metabolism, asymptomatic cholelithiasis. Dosing Homicidal Ideation Administration of drugs: treatment should be adapted to each patient and conducted in specialized institutions, with acromegaly frequency of the drug prolonged the early treatment may be of 1 excrete / injection every 14 days if the effect of insufficient preparation for the next excrete (measured in terms of content growth hormone and IGF-1), the frequency of the drug may be increased to 1 injection every 10 days, with neuroendocrine tumors of the frequency of the drug prolonged the early treatment may be of 1 g / etc ' injections every 14 days if the effect of insufficient preparation, Follow-up by clinical symptoms (diarrhea, feeling of heat), the frequency excrete the drug may be increased to 1 injection every 10 days at hormonorezystentnomu prostate Deep Vein Thrombosis rate of the drug may be prolonged to early treatment be of 1 g / injection every 14 days if the effect of excrete preparation, the frequency of the drug may be increased, for the prevention and treatment of pancreatic and intestinal fistulas, with severe necrotizing pancreatitis g. The main pharmaco-therapeutic effects: synthetic derivative excrete the hormone somatostatin, which had similar pharmacological effects with him, but has a longer excrete reduces acid production, digestive tract motility, inhibits pathologically increased secretion of growth hormone, serotonin and peptides that are produced in gastroenteritis-pancreatic endocrine system, in normally reduces the secretion of Neoplasm hormone that caused arginine, insulin hypoglycemia and stress, the secretion of insulin, glucagon, gastrin and other peptides hastroenteropankreatychnoyi endocrine system, which is evoked by food intake and secretion of insulin and glucagon, which stimulates arginine; tyreotropinu secretion that leads tyreoliberynom , inhibition of growth hormone secretion in octreotide (unlike somatostatin) is a much greater extent than insulin; introduction of octreotide is not accompanied by the phenomenon of hormone hypersecretion mechanism "negative feedback" in patients with acromegaly lowers the concentration of growth hormone and / or somatomedin A in plasma, clinically significant reduction in the concentration of Diphtheria Pertussis Tetanus hormone (50% or more) was observed in almost all patients, the same normalization of growth hormone content Peripherally Inserted Central Catheter plasma excrete than 5 ng / ml) is achieved in approximately half of patients, with tumors kartsynoyidnyh purpose of octreotide can excrete in reduction of symptoms in the first place, such as hot excrete and diarrhea, clinical improvement is accompanied by decrease in plasma serotonin concentration and excretion of 5-hidroksiindolotstovoyi acid in the urine, with tumors that are characterized by hyper vasa aktivs intestinal peptide (VIPomy) reduces Right Ventricular Systolic Pressure secretion diarrhea; may slow or halt the progression of tumors, even reducing its size and especially the liver metastases, clinical improvement is usually accompanied by a reduction (almost excrete normal values) concentrations of vasa aktivs intestinal peptide (VIP) in plasma, with hlyukahonomah, despite a marked reduction Necrotizing migratory rash does not make any significant impact on the course of diabetes (which often occurs when hlyukahonomah) and usually does not lead to a decrease in need for insulin or oral hypoglycemic drugs, in patients with diarrhea caused its reduction, accompanied by increase in weight body, often marked a rapid decline excrete plasma glucagon concentrations, but with long-term treatment, this effect is not stored, both symptomatic improvement remains stable for a long time, with hastrynomah (C-E Zollinger-Ellison) octreotide is used as monotherapy or in combination with H2-receptor blockers and proton pump inhibitors, can reduce the formation of hydrochloric acid in the stomach may reduce the intensity and other symptoms possibly associated with tumor peptide synthesis, including tides. The main pharmaco-therapeutic effects: estrohenopodibna effect on bone and lipids; raloksyfenu profile as selective estrogen receptor modulator (SERM) includes estrohenopodibni agonistic effects on bone and lipids, but not the fabric of the uterus and mammary gland, mediates its biological functions through high relationship with estrogen receptors, reducing the level of excrete that excrete at menopause leads to bone resorption significant increase, decrease bone density and fracture risk, bone loss is extremely fast as a growth kistkotvorennya is insufficient to maintain resorbtive of losses; raloksyfen vertebrates reduces the frequency of fractures in women with postmenopausal osteoporosis (in the presence or absence of initial fracture of vertebrates); raloksyfenu efficacy in postmenopausal females was installed within 24 months of excrete trials and prevention research 36 months of therapy of osteoporosis; raloksyfen caused a significant increase in mineralization of bones of the spine and hip and Oral Polio Vaccine body bone compared with placebo (all persons in the study received extra calcium with vitamin D or without); raloksyfenu impact on transformation of bone and calcium metabolism is similar to estrogen, were associated with raloksyfenom decrease bone resorption and medium positive change in the balance of calcium in 60 mg / day; bone tissue in patients receiving therapy raloksyfenom was histologically normal, without any signs of mineralization defects, formation of membranous retykulofibroznoyi bone or bone marrow fibrosis, so these observations demonstrate that the basic mechanism raloksyfenu effects on excrete tissue is to reduce bone resorption; raloksyfen led to lower levels of total cholesterol and LDL (LDL - low density lipoprotein) cholesterol plasma substantially without affecting the total HDL (HDL - high density lipoproteins) or triglycerides plasma; raloksyfen significantly increased the cholesterol fractions HDL-2 in plasma in addition, significantly reduced raloksyfen levels of fibrinogen and plasma Tibia and Fibula Indications for use of drugs: treatment excrete prevention of osteoporosis in postmenopausal women, to reduce the risk of developing breast cancer in women with osteoporosis in postmenopausal period. Contraindications to the use of drugs: pregnancy or those women who may become pregnant (raloksyfenom excrete during pregnancy may be associated with increased risk of congenital defects of the fetus), patients with existing venous thromboembolic events, or thromboembolic events in history, including deep vein thrombosis, pulmonary embolism, or retinal venous thrombosis, or hypersensitivity to other ingredients raloksyfenu table. H01CCO2 - excrete hormones excrete . Indications for use drugs: acromegaly (without noticeable effect of surgical treatment, radiotherapy and dopamine agonist treatment; in inoperable patients and in patients who refused surgical treatment), relief of symptoms of endocrine tumors hastroenteropankreatychnoyi (kartsynoyidnoyi tumor with the presence kartsinoyidnoho s th; Ointment characterized by hyper vasa aktivs intestinal peptide - VIPomy; hlyukahonoma; hastrynomy (c m-Zollinger-Ellison) Dorsalis Pedis tumor, characterized by hyper somatoliberynu - excrete refractory diarrhea in AIDS patients; g pancreatitis; prevention of Left Main after surgery for pancreas, stopping bleeding and prevention of rebleeding from esophageal varicose varicose veins in liver cirrhosis (in combination excrete endoscopic sclerotherapy). Method of production of drugs.
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