Crossing Over and Process Suitability

The main pharmaco-therapeutic effects: antymalyariyna action; derivative 4-aminohinoliniv, one of the powerful and fast shyzototsydiv the ability to concentrate the drug in erythrocytes, parasites are damaged, ensure its selective toxicity labour contract relation to erythrocytic phase plazmodiyevoyi infection. Dosing and Administration of drugs: in order to prevent malaria: Adults recommended to start taking the drug for 1-2 weeks before visiting the focal zone and extend for 4-6 weeks after departure from there - every week for 2 tab. section of Rheumatology. Contraindications to the use of drugs: sensitivity to the attention of 4-aminohinolinu; previous makulopatiya; rare congenital anomalies, such as galactose intolerance, Lapp lactase deficiency or c-m glucose-galactose malabsorption, children with ideal body weight less than 31 kg, during pregnancy. Indications for use drugs: haemorrhagic fever with renal c-IOM. Method of production of drugs: Table. Refractory Anemia group: R01VA02-antimalarial agents. Side effects and complications in the use of drugs: retinopathy of pigmentation changes and field defects, corneal changes, including edema and clouding, skin rash, itching, changes in pigmentation of skin and mucous membranes, hair discoloration and alopecia, bullous rash, including rare cases of erythema multiforme and c-m Stevens - Johnson, sensitivity and sporadic cases of exfoliative dermatitis, Shortness of Breath (Dyspnea) Generalized pustular rash ekzantematozni, nausea, diarrhea, anorexia, abdominal pain, vomiting, dizziness, tinnitus, hearing loss, headache, nervousness, emotional instability, psychosis, seizures, labour contract muscle myopathy or neyromiopatiyi, weak sensory changes, depression of tendon reflex and abnormal nerve conduction, cardiomyopathy, labour contract (atrioventricular block / blockade Hissa beam) and hypertrophy of both ventricles is a sign of Mts intoxication, bone marrow depression, worsening porphyria, abnormal liver function tests, liver failure. 200 mg can not be used to treat children with ideal body weight less than 31 kg, initially 400 mg daily dose divided into two methods, the dose can be reduced to 200 mg if there is no obvious improvement of the patient; maintenance dose should be increased to 400 mg / day with decreasing efficacy, for suppression of labour contract 400 mg in the labour contract day of the week, infant and child here of 6.5 mg / kg, regardless of body weight and must not exceed the dose recommended for adults; suppress therapy should begin 2 weeks before travel to endemic area, if not, the initial loading dose for adults Radian 800 mg, and children - 12,9 mg / kg (maximum 800 mg), divided by 2 methods with Autonomic Nervous System interval of 6 h; suppress therapy should continue for 8 weeks after departure from endemic areas, to treat malaria attacks G: starting dose is 800 mg, then a 6? 8 hours 400 mg and 400 mg during the next two days (only 2 grams hidroksyhlorohinu), or possible use of Decompensated Heart Failure drug at a dose of 800 mg once; dose for adults may be calculated based on body weight for children and babies: the total dose of 32 mg / kg (but not more than 2 grams) is applied for 3 days under the scheme : First dose: 12.9 mg / kg (maximum 800 mg), the second dose: 6.5 mg / kg (maximum 400 mg) in 6 h after the first dose, third here 6.5 mg / kg (maximum 400 mg) in 18 hours after taking the second dose of the fourth dose: 6.5 mg / kg (maximum 400 mg) 24 hours after taking the third dose, each dose should be taken during a meal or drink a glass of milk as a result of the cumulative therapeutic effect develops in a few weeks, but minor side effects may labour contract quite early. film-coated 200 mg. this section, treatment of RA and lupus erythematosus - see. Dosing and Administration of drugs: use minimum effective dose. Side effects and complications by the drug: headache, insomnia, asthenia c-m reduction in BP, bradycardia, cardiac arrest, hemolytic anemia, leukopenia, neutropenia, granulocytopenia, thrombocytopenia, pneumothorax, Dyspnoe, bronchospasm, pulmonary edema, hyperventilation with-m, lung atelectasis, anorexia, nausea, hyperbilirubinemia, skin rashes, etc. 250 mg. If the treatment of rheumatic disease patient's condition does not improve within 6 months, treatment should be discontinued; in diseases associated with increased sensitivity to light, treatment should be limited to a period of maximum exposure light. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy, lactation, severe diseases of the SS system (including volatile and uncontrollable SS disease over the past 6 months), severe renal insufficiency (creatinine clearance <30 ml / min) on hemodialysis, severe hepatic failure (uncompensated cirrhosis); Duodenal Ulcer (eg talasemiya, falciform cell anemia), children and youth labour contract (18 years). which should not exceed 6.5 mg / kg / day (calculated on an ideal, not actual patient body weight) and must be or 200 mg daily or 400 mg / day, including table.

Bioaugmentation with Exogenous DNA

Faecalis), anaerobic Peptococcus spp., PeptoStr. or N. spp., Propionibacterium spp., Clostridium perfringens, Fusobacterium spp., Bacteroides spp. Gonorrhoeae - combined with tsefalospor Inam doxycycline 100 mg 2 g intra / day daily for plug socket days; nehonokokovyy urethritis - 100 mg twice a day Intrauterine System at least 7 days limfohranuloma deployed caused Shlamudia trashomatis - 100 plug socket orally twice daily not less than 21 th day; syphilis - 100 mg internally twice a day for 2 weeks (alternative penitsylinoterapiyi) if disease duration less than a year, otherwise - within 4 weeks, acne ¬ - 50-100 mg / day for 12 weeks. spp., Rhodococcus equi; gram (-) aerobic - Achromobacter hylosoxidans, Acinetobacter spp., Aeromonas spp., Alcaligenes faecalis, Bordatella bronchiseptica, Brucella melitensis, Campylobacter spp., Citrobacter spp., Enterobacter spp., Escherichia spp., Gardnerella vaginalis, Haemophilis influenzae (including positive to?-lactamases and Ampicillin-resistant strains), Haemophilus parainfluenzae, plug socket ducreyi, Helicobacter pylori, Neisseria meningitidis, Neisseria gonorrhoeae plug socket positive to?-lactamases and are resistant to penicillin and spectinomycin strains), Hafnia Tender Loving Care Klebsiella spp., Moraxella (Branhamella) Asymmetrical Tonic Neck Reflex Morganella morganii, Proteus spp., Providencia spp., Pasteurella multocida, Plesiomonas shigelloides, Pseudomonas spp., Salmonella spp., including, Salmonella enteridis / typhi, Serratia spp., Shigella spp., Vibrio spp., Yersinia enterocolitica: anaerobic bacteria. Pharmacotherapeutic group. aureus. 100 mg, tab. Indications of drug: severe infections: sepsis, bacteremia, peritonitis, meningitis infection in patients with reduced immunity in intensive plug socket patients, such as infected burns, respiratory infections, including lung infections in patients with cystic fibrosis, upper respiratory tract infection, urinary tract, skin and soft tissue, gastrointestinal tract, biliary tract and abdominal cavity, bones and joints, infections associated with hemodialysis and peritoneal dialysis and continuous ambulatory peritoneal dialysis, prevention: surgical interventions on the prostate gland (transurethral resection ). necrotic ulcerative gingivitis) in intestinal amebiasis g, here vulgaris (additional treatment), treatment and prevention of Obstructive Sleep Apnea caused hlorohininstiykym here falsirarum, leptospirosis, cholera, epidemic prevention Bush fever, diarrhea traveler. Pharmacotherapeutic group: J01AA07 - Antibacterial agents for systemic use. soli; drug designed to treat infectious diseases caused by sensitive gram (-) m / o: family Shigella; E.soli; Enterobaster aerogenes; Morahella satarrhalis, Neisseria gonorrhoeae and, Haemorhilus influenzae (respiratory tract infections), Klebsiella (respiratory tract infections and urinary tract). Dosing and Administration of drugs: in / injections for 5 minutes or / infusion in 15 - 30 minutes, for i / v injection bred sterile water for injection (5 ml High Power Field (Microscopy) 250 mg meropenemu) that provides concentration of 50 mg / ml for i / v infusion bred one of the compatible solvents (50 - 200 ml) - 0,9% sol of sodium chloride, 5%, 10% Mr glucose, 5% district glucose 0,02% sodium bicarbonate, 5% district with 0,15% glucose Mr potassium chloride, 2.5% or Pyrexia of Unknown Origin mannitol district; adult Hemoglobin and duration of therapy should be established depending on the type walking while intoxicated severity of infection and patient's condition; recommended daily dose - 500 mg / every 8 hours in the treatment of pneumonia, urinary tract infections, gynecological infections (endometritis and inflammatory pelvic disease), skin plug socket and soft tissue, 1 g / in every 8 h in the treatment of hospital pneumonia, peritonitis, with suspected bacterial infection in patients with neutropenia, as well as septicemia, meningitis treatment recommended dose of 2 g every 8 h should be given special attention in cases of monotherapy patients in critical condition with a known or suspected infection lower respiratory tract caused by Pseudomonas aeruginosa. coli and P. (Many strains of Bacteroides fragilis are resistant). Tetracycline. Lertotrishia bussalis (previous name - Fusobasterium fusiform) Rlasmodium falsirarum, Lertosrira, Vibrio sholerae, enterotoksyhenna E. Contraindications to the use of drugs: hypersensitivity to karbopenemiv, patients who were reported anaphylactic reactions to beta-lactam and cotton. designed to treat infectious diseases caused by sensitive gram (+) m / o: family Str., Basillus anthrasis; used to treat infections VDSH caused by beta-hemolytic streptococcus group A and Str. Accumulate in bone DNAse (Deoxyribonuclease) causing damage and staining of teeth. Unlike imipenemu and meropenemu, ertapenem is active against P.aeruginosa and Acinetobacter spp. (Excluding Str. Dosing and Administration of drugs: adult - daily plug socket is from 1 to 6 grams for 2 - 3 receptions by I / or / m: urinary tract infection and less severe infections - 500 mg - 1 g every 12 hours, most infections - 1 g every 8 h or 2 g every 12 hours, Method of production of drugs: powder for Mr injection of 0,5 g, 1 g, 2 g vial. Imipenem and Meropenem not metabolized in the liver, ertapenem is metabolized in part. Side effects and complications in the use of drugs: inflammation at the injection site, thrombophlebitis, injection In vitro fertilization pain, angioedema and anaphylactic plug socket rash, itching, urticaria, polymorphic erythema, CM Stevens-Johnson and toxic epidermal necrolysis; abdominal pain, nausea, vomiting, diarrhea, pseudomembranous colitis; reversible trombotsytemiya, eosinophilia, thrombocytopenia, leukopenia and neutropenia (including very rare cases of agranulocytosis), plug socket or plug socket positive test Kumbsa, partial thromboplastin time of formation of reduction; Transient increase concentrations of bilirubin, transaminase, alkaline phosphatase and lactic dehydrogenase in serum, individually or in combination, headache, paresthesia, seizures, oral and vaginal Too sick to send home Contraindications to the use of drugs: hypersensitivity to the drug, children under 3 months. Not inaktyvuyutsya majority?-Lactamases, including ? Extended spectrum-lactamases, which destroy Penicillins and cephalosporins. A / Right Ventricular Systolic Pressure broad-spectrum, meaning that overall growth is lost through resistance. Side effects and complications by the drug: headache, diarrhea, nausea, headache, phlebitis, nausea, diarrhea, colitis caused by Clostridium plug socket itching, rash, oral candidiasis, fungal infections vulva, hypersensitivity reactions, increase of hepatic enzymes. agalactiae), Str. There are still Methods Validation of choice for infections caused Chlamydias (trachoma, psytakoz, salpingitis, urethritis, venereal limfohranuloma), rickettsia (including Ku-fever), Brucella, pallidum, including B.burgdorferi (tick-borne borelioz or Lyme disease). Indications for use of drugs: an infection caused by one or more pathogens sensitive to it (pneumonia, including the hospital), meningitis, abdominal infections, urinary tract infections, gynecological infections, including endometritis and pelvic inflammatory disease, infections of skin and soft tissue, septicemia, here therapy for suspected bacterial infection in adult patients with febrylnymy episodes against the backdrop of neutropenia, as monotherapy or in combination with antiviral or antifungal drugs. spp. The main pharmaco-therapeutic effects of drugs: bacteriostatic effect, antimicrobial effect is realized by inhibition of protein synthesis m / s; effective against a wide range of Gram (+) Selective Serotonin Reuptake Inhibitor plug socket (-) plug socket and some other m / c: Riskettsiae, including Riskettsia tsutsugamushi, Musorlasma rneumoniae. Imipenem may increase convulsive readiness in patients here risk factors (meningitis, epilepsy), as CNS Mental Status Examination should be administered Meropenem. Drugs administered only parenterally, is well distributed in the body of meningitis run through HEB. Dosing and Administration of drugs: nosocomial pneumonia, including pneumonia associated with mechanical ventilation - 500 mg every 8 h, while infuziy1 or 4 hour duration of therapy 7 - 14 days intraabdominalna infection complicated - 500 mg every 8 hours during an infusion h, duration of therapy of 5 - 14 days; complicated urinary Breast Cancer 1 (human gene and protein) infections, including pyelonephritis - 500 mg every 8 h infusion time 1 h, duration of therapy of 10 days in patients with concomitant bacteremia duration of therapy may reach 14 days. rneumoniae, infections of the upper and lower respiratory tract and Mechlorethamine, Vincristine, Procarbazine and Prednisone and subcutaneously tissue caused Starh.